Pre-Conference Workshops

Workshop A

Tuesday 23rd April 2024

9:30 AM to 12:30 PM

Uncovering the Latest Advancements in Technology for Optimizing the Discovery of Next Generation Peptides

  • Lauren Goodrich Vice President, Therapeutic Discovery, Nimble Therapeutics
  • Cameron Pye Chief Executive Officer, Unnatural Products

Synopsis

This workshop aims to showcase the future of peptide discovery, emphasizing AIdriven computational design and advanced screening technologies alongside optimization platforms and in-vivo peptide display. Gain invaluable insights into these cutting-edge approaches, leveraging them to accelerate peptide discovery, design, and development.

• Advancing in-vivo phage display for identification of organ-specific peptides for high selectivity targeting

• Utilizing artificial intelligence and machine learning for predictive peptide design and for optimizing peptide properties • Showcasing advancements and breakthroughs in peptide structural biology with CRYO-EM

• Exploring state-of-the-art high-throughput screening platforms tailored for peptides

Lunch 12:30 PM - 1:30PM

Workshop B

Tuesday 23rd April 2024

1:30 PM to 4:30 PM

Improving Cell Permeability & Intracellular Selectivity of Peptides to Unlock a Realm of New Intracellular Targets

Synopsis

This workshop aims to provide a comprehensive exploration of strategies to enhance the cell permeability of peptides. Attendees will gain insights into innovative structural modifications and nanocarrier-based strategies, empowering them with knowledge to advance peptide delivery into cells for various therapeutic interventions.

• Exploring chemical modifications and structural alterations to improve cell penetration

• Novel peptide designs and conjugation approaches for increased cellular uptake

• Discussing transporter-mediated and nanocarrier-based approaches for facilitating cellular internalization

• Utilizing cell-penetrating peptides (CPPs) and peptide nanocarriers for efficient delivery

• Harnessing membrane transporters and peptide-functionalized nanomaterials for intracellular transport

• Examining advancements in nanotechnology for targeted intracellular peptide delivery

• Uncovering challenges and opportunities in translating membrane-permeable peptides into clinical applications

End of Pre-Conference Workshop Day