Roundtable Discussion: From Discovery to Translation; Developing Cell Permeable & Orally Bioavailable Peptides with Optimal Pharmacology & DMPK
- Modifying amino acids to optimise target selectivity and cell membrane permeability to achieve the right pharmacology
- Modelling protein-protein interactions in the discovery to translate into the preclinical setting
- Analysing the pharmacokinetic and biodistribution properties of highly soluble orally bioavailable peptides to ensure efficacy when entering the clinic